2026-10-13T01:35:22Z
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oai:figshare.com:article/34017640
2026-09-28T17:52:37Z
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<p>Developmental expression of ALG-related genes.</p>
Amanda A. G. Ferreira (25132828)
Sergio Córdoba (645937)
Raghuvanshi Rajesh (25132831)
Ben Jiwon Choi (25132834)
Claude Desplan (45436)
Cell Biology
Genetics
Neuroscience
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Cancer
Hematology
Plant Biology
innovative computational approach
genetic markers expressed
div >< p
subcellular mrna compartmentalization
optic lobe glia
two large single
detailed transcriptomic analysis
identify mrna species
glial diversity observed
adult visual system
glial cell bodies
glial cell types
understand glial development
visual system
cell mrna
cell bodies
glial types
glial cells
glia types
adult stages
cell class
cell atlas
neuropil glia
chiasm glia
work provides
transcriptionally appear
pupal stages
helps explain
gradually change
drosophila </
distinct mrnas
differentially localized
developmental trajectories
developmental single
comprehensively annotated
also present
allowed us
<p>UMAP of medulla neuropil glia (mng) cells showing the expression of transmembrane protein encoding genes previously described as relevant for ALG mng morphogenesis <b>(A, B)</b> or as ALG-specific markers <b>(C)</b>. While <i>lapsyn</i> and <i>htl</i> expression do not show ALG-specific expression, <i>wun2</i> transcription strongly correlates with ALG fate after the bifurcation (upper branch) <b>(D, D’)</b> Heatmap showing cell surface and secreted protein encoding genes with differential expression at early (right) mid (center) and late (left) pseudotime points for medulla neuropil ALG (D) and EG glia (D’) developmental trajectories.</p> <p>(TIFF)</p>
2026-09-28T17:57:37Z
Image
Figure
10.1371/journal.pbio.3004015.s008
https://figshare.com/articles/figure/_p_Developmental_expression_of_ALG-related_genes_p_/34017640
CC BY 4.0