2026-10-14T12:39:02Z
https://api.figshare.com/v2/oai
oai:figshare.com:article/34017481
2026-09-28T17:51:30Z
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month_year_09_2026
<p>Comparison of cutaneous cytokine and chemokine expression between untouched control and tick attachment skin.</p>
Chanakan Suwanbongkot (14290412)
Ingeborg M. Langohr (10895024)
Killian Z. Brewer (25132813)
Robert A. Barrington (25132816)
Kevin R. Macaluso (8998328)
Medicine
Microbiology
Environmental Sciences not elsewhere classified
Ecology
Immunology
Biological Sciences not elsewhere classified
Infectious Diseases
spotted fever group
quantifiable bacterial load
dominant cell type
amblyomma maculatum .</
late feeding stage
>- infected skin
mouse skin delivered
144 hours ).
cutaneous immune response
rickettsia parkeri ,</
post tick attachment
cutaneous host response
tick infection status
144 hours
tick attachment
infection status
immune responses
early stage
host response
rickettsia </
infected tick
144 hpa
parkeri </
vector saliva
rickettsial pathogenesis
rickettsial infection
rapid dissemination
preventive strategies
lymph nodes
internal tissues
inflammatory activation
infection site
infection kinetics
hpa ),
histopathological analysis
enhanced levels
emerging tick
elicited based
early events
dissemination kinetics
dependent inflammation
data show
chemokine profiling
borne pathogen
<p>Skin samples from the untouched control (UNC) and <i>Rickettsia</i>-uninfected tick (UNT) attachment site were collected at 3, 48, and 144 hours post-tick attachment (hpa) to evaluate the cytokine and chemokine expression. Each symbol (diamond and triangle) represents a single mouse skin biopsy from the tick attachment site, with a total of 8 mice/timepoint/group. The data are represented as the mean ± SEM. Statistical significance was assessed using two-way ANOVA followed by Tukey’s multiple-comparison test, with a single-pool variance (*<i>p</i> < 0.05; **<i>p <</i> 0.01; ***<i>p <</i> 0.001).</p> <p>(ZIP)</p>
2026-09-28T18:01:26Z
Dataset
Dataset
10.1371/journal.ppat.1014626.s003
https://figshare.com/articles/dataset/_p_Comparison_of_cutaneous_cytokine_and_chemokine_expression_between_untouched_control_and_tick_attachment_skin_p_/34017481
CC BY 4.0