2026-10-06T18:51:20Z
https://api.figshare.com/v2/oai
oai:figshare.com:article/34017191
2026-09-28T17:42:58Z
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month_year_09_2026
<p>WAO-ExM image of a 4× expanded adult heart, showing <i>Tg(tcf21:nuceGFP)</i>-labeled epicardial cells.</p>
Hsiao-Yuh Roan (25132784)
Xuejiao Tian (20523980)
Wei-Chen Chu (450265)
Chia-Ming Lee (12987725)
Hsin Chen (2365045)
Fiorency Santoso (25132787)
Chung-Han Wang (19334639)
Yu-Hsiu Liu (4254004)
Uday Kumar (16457565)
He-Yun Hsiao (25132790)
Chiou-Hwa Yuh (253039)
Bi-Chang Chen (2656468)
Chen-Hui Chen (739721)
Biophysics
Biochemistry
Medicine
Microbiology
Cell Biology
Genetics
Molecular Biology
Physiology
Biotechnology
Evolutionary Biology
Chemical Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Developmental Biology
Cancer
Infectious Diseases
Plant Biology
Computational Biology
using transgenic reporters
temporally concentrated burst
overall body growth
monitor individual cells
monitor diseased livers
linear growth regimen
label hepatocyte nuclei
findings bridge micrometer
every hepatocyte within
5 mm thickness
cell number increases
cell number increased
organ expansion microscopy
scale cell behaviors
embryonic growth period
bona fide single
scale organ growth
adult vertebrate organs
also utilized wao
embryonic period
organ scale
adult organs
cell resolution
cell proliferation
organ single
wide process
toto single
tissue architecture
resolved visualization
lineage tracing
integrated workflow
including heart
generalizable platform
fully resolved
clonal organization
206 hepatocytes
<p>A total of 4 × 4 tiles and 298 z-steps were acquired, covering a three-dimensional volume of 6.4 × 6.4 × 3.0 mm<sup>3</sup> in the sample space.</p> <p>(MP4)</p>
2026-09-28T18:01:19Z
Dataset
Media
10.1371/journal.pbio.3004007.s012
https://figshare.com/articles/media/_p_WAO-ExM_image_of_a_4_expanded_adult_heart_showing_i_Tg_tcf21_nuceGFP_i_-labeled_epicardial_cells_p_/34017191
CC BY 4.0