2026-10-10T09:13:52Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34015603 2026-09-28T17:23:52Z category_7 category_19 category_21 category_64 category_106 category_122 category_132 portal_5 item_type_3 month_year_09_2026

<p>Summary translation rates by multiple definitions.</p> Timothy R. Entwistle (25132513) William R. Cowey (25132516) Eliza Stokoe (25132519) John P. Stone (9176108) James E. Fildes (9176126) Medicine Pharmacology Biotechnology Cancer Science Policy Mental Health Infectious Diseases two reviewers blinded physical interventions ). open science framework may substantially overestimate 9 &# 8211 847 records identified 6 %, likely 2 &# 8211 small rodent models routine clinical use specified regulatory categories small animal models market safety concerns conflates trial entry 22 march 2022 human clinical trials 6 %; 95 market safety outcomes human therapeutic outcomes novel preclinical therapies class regulatory approval animal models clinical trials safety outcomes market safety human approval regulatory approval regulatory reality preclinical promise novel first therapeutic intervention therapeutic development xlink "> via pubmed third adjudicating syrcle tool syrcle guidance synthesised descriptively section s3 s1 file proportion progressing predictive validity osf (< market analysis guinea pigs full strategy effect approvals <p>Summary translation rates by multiple definitions.</p> 2026-09-28T17:23:42Z Dataset Dataset 10.1371/journal.pone.0358773.t005 https://figshare.com/articles/dataset/_p_Summary_translation_rates_by_multiple_definitions_p_/34015603 CC BY 4.0