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oai:figshare.com:article/34009212 2026-09-28T05:36:14Z category_374 portal_316 item_type_3 month_year_09_2026

Table 1_The effect of exercise snacks on cardiorespiratory fitness, body composition, metabolic health, and muscle strength in sedentary individuals: a systematic review and meta-analysis.docx Kai Qi (1731952) Qiyi Wang (736292) Decheng Xu (7507082) Adam Kawczyński (13001783) Aiguo Chen (4238587) Clinical and Sports Nutrition body composition cardiorespiratory fitness exercise snacks metabolic health muscle strength sedentary Objective<p>This systematic review and meta-analysis aimed to investigate the effects of exercise snacks (ES) on cardiorespiratory fitness, body composition, metabolic health, and muscle strength in sedentary individuals.</p>Methods<p>From database inception to February 5, 2026, four international databases (PubMed, Web of Science, SciELO, and the Cochrane Central Register of Controlled Trials) and one Chinese database (China National Knowledge Infrastructure) were searched. The GRADE approach was used to assess the certainty of evidence, while the Cochrane Risk of Bias tools (RoB 2) and Risk of Bias In Non-randomized Studies of Intervention (ROBINS-I) were applied to evaluate the quality of randomized controlled trials and non-randomized studies, respectively. The pooled effects of study outcomes were estimated using a random-effects model based on meta-analysis. Subgroup analyses and meta-regression were conducted to explore potential moderating variables.</p>Results<p>A total of 22 studies involving 994 participants were included. The meta-analysis showed that ES significantly improved VO_2max (Hedges’ g = 1.24, 95% CI: 0.53 to 1.95, p < 0.001, I² = 75.0%, τ² = 1.13), VO_2peak (Hedges’ g = 0.63, 95% CI: 0.05 to 1.22, p < 0.05, I² = 55.0%, τ² = 0.19), triglycerides (Hedges’ g = 1.05, 95% CI: 0.05 to 2.06, p < 0.05, I² = 84.0%, τ² = 0.65), and blood glucose (Hedges’ g = −0.83, 95% CI: −1.51 to −0.15, p < 0.05, I² = 78.0%, τ² = 0.69) in sedentary populations. However, significant publication bias was detected for VO_2max, and the trim-and-fill analysis yielded an adjusted effect estimate that was no longer statistically significant (Hedges’ g = 0.62, 95% CI: −0.59 to 1.83, p = 0.32). No significant differences were observed in body fat, muscle mass, strength, or insulin levels.</p>Conclusion<p>As a short-duration, high-frequency intervention, ES may improve cardiorespiratory fitness and certain metabolic health indicators in sedentary individuals. However, the finding for VO_2max should be interpreted cautiously because the trim-and-fill adjusted estimate was not statistically significant, suggesting that publication bias may have influenced the observed effect. It provides a potentially sustainable and effective exercise intervention strategy for sedentary individuals.</p>Systematic review registration<p>PROSPERO (CRD420261347411).</p> 2026-09-28T05:36:14Z Dataset Dataset 10.3389/fnut.2026.1883923.s001 https://figshare.com/articles/dataset/Table_1_The_effect_of_exercise_snacks_on_cardiorespiratory_fitness_body_composition_metabolic_health_and_muscle_strength_in_sedentary_individuals_a_systematic_review_and_meta-analysis_docx/34009212 CC BY 4.0