2026-10-07T16:00:51Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34004814 2026-09-27T12:39:41Z category_24166 category_24139 item_type_3 month_year_09_2026

Gene Expression Dataset of Tazemetostat-Treated SW-1736 Cells Using the WNT Signaling RT² Profiler PCR Array Cigir Biray Avci (25076323) Maryam Sabour Takanlou (18962360) Leila Sabour Takanlou (18962357) Behrouz Shademan (25115914) Nur Selvi Gunel (9679011) Huseyin Aktug (12757826) Mehmet Erdogan (25115919) hatice ozisik (25115911) Signal transduction Cell development, proliferation and death Tazemetostat SW-1736 EZH2 Anaplastic thyroid cancer Wnt Signaling Pathway Genes RT2 profiler PCR array Gene expression <p dir="ltr">This dataset contains the raw and processed gene expression data generated from SW-1736 anaplastic thyroid cancer cells treated with the EZH2 inhibitor tazemetostat (EPZ-6438). Gene expression changes in the WNT signaling pathway were evaluated using the Qiagen RT² Profiler PCR Array Human WNT Signaling Pathway (PAHS-043Z) and the Roche LightCycler 480 real-time PCR system. The dataset includes raw Cp values obtained from control SW-1736 cells and cells treated with tazemetostat for 24, 48, and 72 hours, together with the processed gene expression analysis. Relative gene expression was evaluated using the comparative Ct/Cp (2^-ΔΔCt) method. The deposited files provide the underlying gene expression data supporting the WNT signaling pathway analyses reported in the associated manuscript, “Investigation of the effect of the EZH2 inhibitor Tazemetostat on apoptosis and the WNT signaling pathway in anaplastic thyroid cancer cells."</p> 2026-09-27T12:39:41Z Dataset Dataset 10.6084/m9.figshare.34004814.v1 https://figshare.com/articles/dataset/Gene_Expression_Dataset_of_Tazemetostat-Treated_SW-1736_Cells_Using_the_WNT_Signaling_RT_Profiler_PCR_Array/34004814 CC BY 4.0