2026-10-12T15:46:51Z https://api.figshare.com/v2/oai

oai:figshare.com:article/34004235 2026-09-27T03:24:19Z category_13 portal_81 item_type_3 month_year_09_2026

Additional file 1 of Scalable clinical proteomics from DNA/RNA extraction flowthroughs enables integrated proteogenomic profiling from a single cancer biopsy Filip Mundt (124054) Annelaura Bach Nielsen (25115382) Juanjuan Wang (1807810) Josephine Kerzel Duel (25115385) Christina Westmose Yde (25115388) Martina Amnitzbøll Eriksen (25115391) Ulrik Lassen (576329) Finn Cilius Nielsen (30909) Kristoffer Rohrberg (10431524) Matthias Mann (13750) Genetics systematically evaluated whether single clinical sample routine clinical workflows results optimized single integrated proteogenomic studies guide therapy selection associated biological signatures assessed sample stability scalable clinical proteomics qiagen allprep system proteins largely represent derived biopsy material rna extraction provide rna extraction kits residual protein fractions 000 protein groups metastatic cancer biopsies clinical tumor biopsies qiagen allprep dna precision oncology trial phosphoproteomic analyses identified rna extraction tumor biopsies precision oncology scalable resource largely relied biopsy used advanced cancer translational oncology transcriptomic analyses phosphoproteomic profiling phosphoproteomic measurements dia analyses protein recovery protein integrity typically discarded transcriptomic sequencing throughput analysis therefore emerged term storage signaling pathways samples stored rich flowthrough reliable source peptide cleanup molecular layers integrating proteomic independent acquisition important objective Supplementary Material 1. 2026-09-20T05:00:00Z Dataset Dataset 10.6084/m9.figshare.34004235.v1 https://figshare.com/articles/dataset/Additional_file_1_of_Scalable_clinical_proteomics_from_DNA_RNA_extraction_flowthroughs_enables_integrated_proteogenomic_profiling_from_a_single_cancer_biopsy/34004235 CC BY