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oai:figshare.com:article/34000299 2026-09-25T17:52:35Z category_146 category_7 category_8 category_21 category_272 category_46 category_734 category_64 category_132 portal_5 item_type_3 month_year_09_2026

<p>Performance comparison of disease state classification methods. Our model was evaluated using five-fold cross-validation to classify lung tissue sections into three disease states: asymptomatic infection, acute pulmonary TB, and chronic pulmonary TB. Values in parentheses represent 95% confidence intervals.</p> Usama Sajjad (25111695) Nicholas A. Crossland (5500244) Metin N. Gurcan (5095118) Gillian Beamer (623385) Muhammad Khalid Khan Niazi (5095121) Space Science Medicine Microbiology Biotechnology Environmental Sciences not elsewhere classified Immunology Biological Sciences not elsewhere classified Cancer Infectious Diseases second novel approach granuloma architecture varies based spatial immunoprofiling multiplexed fluorescence images used lung sections results help establish derived results shows balanced immune expression tb ), caused large language model div >< p address knowledge gaps peribronchiolar b cells bronchiolar epithelial cells chronic pulmonary tb acute pulmonary tb mycobacterium tuberculosis </ b cells chronic tb multiplexed immunofluorescence immune cells bronchiolar epithelium tb </ highest immune tb -</ acute tb cells closer study show macrophage proximity low cellularity human responses higher cd4 first developed dysfunctional responses disease state directly studied deep learning better understand automated pipeline approximately 10 analyze data accurate model >), remains <p>Performance comparison of disease state classification methods. Our model was evaluated using five-fold cross-validation to classify lung tissue sections into three disease states: asymptomatic infection, acute pulmonary TB, and chronic pulmonary TB. Values in parentheses represent 95% confidence intervals.</p> 2026-09-25T17:52:22Z Dataset Dataset 10.1371/journal.pone.0358334.t002 https://figshare.com/articles/dataset/_p_Performance_comparison_of_disease_state_classification_methods_Our_model_was_evaluated_using_five-fold_cross-validation_to_classify_lung_tissue_sections_into_three_disease_states_asymptomatic_infection_acute_pulmonary_TB_and_chronic_pulm/34000299 CC BY 4.0