2026-10-10T15:28:58Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33995423 2026-09-25T13:30:03Z category_8 category_14 category_21 category_272 category_69 category_132 portal_63 item_type_3 month_year_09_2026

Photo-Induced Three-Component Radical Trifluoromethylation/Heteroarylation of Alkenes via EDA Complexes Zhijun Zhu (1739134) Xiaopeng Hai (22486888) Yuyu Lv (19115924) Ke-Hu Wang (1456924) Junjiao Wang (11845452) Bo-Sheng Zhang (1433737) Danfeng Huang (650141) Yulai Hu (1456918) Microbiology Molecular Biology Biotechnology Environmental Sciences not elsewhere classified Inorganic Chemistry Infectious Diseases readily available dbu method offers advantages industrially available cf facile postreaction processing economical new avenue containing heterocyclic compounds component radical trifluoromethylation 3 </ sub containing heterocycles trifluoromethyl source study develops stage modification induced three green late fluorescent dyes electron donor complex strategy This study develops a visible-light-induced electron donor–acceptor (EDA) complex strategy, employing the inexpensive and readily available DBU as the electron donor and the industrially available CF₃Br as the trifluoromethyl source, to achieve the trifluoromethylation/heteroarylation of alkenes. This method offers advantages in cost-effectiveness and facile postreaction processing, without requiring transition metals or fluorescent dyes as photocatalysts. Moreover, nitrogen-containing heterocycles such as quinoxalinones, uracils, and pyrazines are all compatible in this transformation through C–H alkylation, providing a convenient and economical new avenue for the green late-stage modification of nitrogen-containing heterocyclic compounds. 2026-09-25T00:00:00Z Dataset Dataset 10.1021/acs.joc.6c01316.s001 https://figshare.com/articles/dataset/Photo-Induced_Three-Component_Radical_Trifluoromethylation_Heteroarylation_of_Alkenes_via_EDA_Complexes/33995423 CC BY-NC 4.0