2026-10-13T06:57:29Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33995202 2026-09-29T12:31:01Z category_36833 category_30881 portal_1132 item_type_3 month_year_09_2026

Data and files for "Drosophila Cryptochrome C-terminus binds FAD to mediate magnetosensitivity." Daniel Kattnig (21060173) Alex R. Jones (25110332) Moona Kurttila (25110334) Alex Hoose (25110342) Noboru Ikeya (25110353) Adam Bradlaugh (25110355) Anna L. Munro (25110358) Richard A. Baines (25110360) Charalambos P. Kyriacou (25110361) Susanna Campesan (20337831) Ezio Rosato (20341071) Jessica L. Ramsay (25110362) Sanjai Patel (25110363) Physical sciences Biological sciences Magnetoreception radical pair electrophysiology Drosophila melanogaster protein binding molecular dynamics flavin adenine dinucleotide <p dir="ltr">This is the data for "Drosophila Cryptochrome C-terminus binds FAD to mediate magnetosensitivity", submitted for publication in PNSA Nexus and currently under revision.</p><p dir="ltr">Magnetosensitivity in animals has been proposed to involve a Cryptochrome (CRY)-based radical pair mechanism, although the molecular basis of this process remains unclear. The C-terminal fragment of <i>Drosophila</i> CRY (DmCRY-CT), which lacks the canonical FAD-binding pocket and conserved tryptophan residues associated with the canonical mechanism, is nevertheless sufficient to support magnetosensitivity. This dataset contains all-atom molecular dynamics (MD) simulations investigating the interaction of flavin adenine dinucleotide (FAD) with DmCRY-CT and the effects of mutations selected based on the predicted contribution of specific residues to FAD binding. The deposited simulations provide structural and dynamic information on FAD–peptide interactions across wild-type and mutant systems.</p> 2026-09-29T00:00:00Z Dataset Dataset 10.24378/exe.33995202.v1 https://figshare.com/articles/dataset/Data_and_files_for_Drosophila_Cryptochrome_C-terminus_binds_FAD_to_mediate_magnetosensitivity_/33995202 CC BY