2026-10-11T12:59:31Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33986044 2026-09-24T14:08:35Z category_1 category_4 category_915 category_8 category_21 category_873 category_45 category_931 category_133 portal_63 item_type_3 month_year_09_2026

Flash Communication: Microwave-Assisted Synthesis of 2‑Alkylphenyl-Substituted (NHC)CuCl Complexes Takumi Tsushima (11705798) Sakiha Kobayashi (25104349) Masaaki Nakamoto (1429102) Takuya Michiyuki (7382570) Hiroto Yoshida (1784392) Biophysics Biochemistry Physical Sciences not elsewhere classified Microbiology Biotechnology Chemical Sciences not elsewhere classified Sociology Information Systems not elsewhere classified Plant Biology nmr analyses show conventionally used tetrahydrofuran 2 ‑ alkylphenyl 2 </ sub ortho </ work offers useful strategy sup >< straightforward approach sterically tunable steric properties largely preserving flash communication electronic properties cucl complexes A base-free, microwave-assisted protocol using Cu₂O and NHC·HCl salts is reported, which allows the synthesis of sterically less hindered 2-alkylphenyl-substituted (NHC)CuCl complexes, (SIMe^<i>ortho</i>)CuCl, (SIPr^<i>ortho</i>)CuCl, (IMe^<i>ortho</i>)CuCl and (IPr^<i>ortho</i>)CuCl; the use of dichloromethane in place of conventionally used tetrahydrofuran as a solvent is the key to success. Structural and NMR analyses show that 2-alkylphenyl substitution efficiently modulates the steric properties of the (NHC)CuCl complexes while largely preserving the electronic properties of the NHC ligands. This work offers a useful strategy for designing diverse NHC ligands, providing a straightforward approach to sterically tunable (NHC)CuCl complexes. 2026-09-24T00:00:00Z Dataset Dataset 10.1021/acs.organomet.6c00276.s001 https://figshare.com/articles/dataset/Flash_Communication_Microwave-Assisted_Synthesis_of_2_Alkylphenyl-Substituted_NHC_CuCl_Complexes/33986044 CC BY-NC 4.0