2026-10-12T22:22:25Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33977227 2026-09-23T17:53:07Z category_1 category_915 category_12 category_13 category_16 category_24 category_734 category_61 portal_5 item_type_2 month_year_09_2026

<p>Standard polarization simulation.</p> Michiel Vanslambrouck (11447440) Jef Vangheel (10944795) Ella Linxia Müller (20995764) Bart Smeets (170582) Pierre Gönczy (434319) Rob Jelier (51741) Biophysics Physical Sciences not elsewhere classified Cell Biology Genetics Physiology Evolutionary Biology Biological Sciences not elsewhere classified Developmental Biology stiff contractile filaments nematic structures contribute high spatiotemporal resolution enables par proteins embryo midpoint emerges div >< p contractile nematic structures biochemical mechanisms maintaining approximately 30 min symmetry breaks near domain arrest near cortical material redistribution robust zygotic polarization polarization remains unclear mechanical negative feedback symmetry breaking occurs posterior domain towards dependent contractility regulation asymmetric cell division measured cortical flow tracking myosin foci presumptive posterior pole complete polarization process symmetry breaking cortical flow myosin foci posterior tension domain stabilization cortical architecture anterior domain mechanical role flow direction flow creates mechanical model well understood tension anisotropy surface ruffles posterior domains nearest pole local downregulation establish anterior elegans </ contributed centrosomes balances anterior anisotropic tension actin bundles <p>Foci in green, actin bundles in red, and density in grayscale.</p> <p>(MP4)</p> 2026-09-23T17:59:22Z Dataset Media 10.1371/journal.pcbi.1014792.s010 https://figshare.com/articles/media/_p_Standard_polarization_simulation_p_/33977227 CC BY 4.0