2026-10-12T00:46:40Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33976974 2026-09-23T17:50:56Z category_13 category_24 category_734 category_811 category_106 category_132 portal_5 item_type_3 month_year_09_2026

<p>Lasso sign changes between univariate and multivariate models. This table displays the number of coefficient sign changes between the univariate and multivariate models for each phenotype and the percentage of coefficients in the active-set that switched. UniLasso, by construction, eliminates all such sign reversals; every non-zero coefficient retains the sign of its univariate effect.</p> Joshua Richland (25099428) Tuomo Kiiskinen (8704011) William Wang (5811092) Wenhui Sophia Lu (25099431) Balasubramanian Narasimhan (6444833) Trevor Hastie (195) Manuel Rivas (268944) Robert Tibshirani (196) Genetics Evolutionary Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Science Policy Infectious Diseases stabilize feature selection regression toward variants level target data informing penalty weights guided sparse regression based repository comprising external statistics guide external scores ). recently introduced univariate leverages univariate coefficients prs estimation methods signals guide unilasso ). yielding sparser xlink "> united kingdom standard lasso sign constraints results demonstrate remains competitive prior evidence interpretable models empirical advantages <p>Lasso sign changes between univariate and multivariate models. This table displays the number of coefficient sign changes between the univariate and multivariate models for each phenotype and the percentage of coefficients in the active-set that switched. UniLasso, by construction, eliminates all such sign reversals; every non-zero coefficient retains the sign of its univariate effect.</p> 2026-09-23T17:43:15Z Dataset Dataset 10.1371/journal.pgen.1012314.t002 https://figshare.com/articles/dataset/_p_Lasso_sign_changes_between_univariate_and_multivariate_models_This_table_displays_the_number_of_coefficient_sign_changes_between_the_univariate_and_multivariate_models_for_each_phenotype_and_the_percentage_of_coefficients_in_the_active-s/33976974 CC BY 4.0