2026-10-11T11:45:11Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33975314 2026-09-23T17:27:30Z category_4 category_12 category_15 category_272 category_45 category_734 category_64 portal_5 item_type_3 month_year_09_2026

<p>(a) Evaluation of machine learning model performance on self-reported maternal family history prediction combing structural neuroimaging with mitochondrial haplogroups. (b) Variable importance analysis for top-performing structural neuroimaging and mitochondrial haplogroup models predicting positive self-reported maternal family history.</p> Olivia J. Veatch (9171779) Sreejata Dutta (22905308) Clayton O. Mansel (25099025) Ryan Townley (9986951) Mihaela E. Sardiu (259011) Robyn A. Honea (9704225) Biochemistry Cell Biology Neuroscience Environmental Sciences not elsewhere classified Sociology Biological Sciences not elsewhere classified Cancer vulnerable region linked using machine learning r0 intermediate clade na &# 239 identifying traits associated alzheimer &# 8217 important overall feature important feature correlated known family history family history information important mitochondrial haplogroup unknown family history reduced sample size mitochondrial haplogroups reduced disease </ p high ad risk family history sample size mitochondrial haplogroups feature importance often unknown mitochondrial genetics mitochondrial data risk stratification performed best origin effects normal cognition model optimization minimal impact informative variables imaging alone hyperparameter tuning fold cross findings reinforce complicating identification brain atrophy 129 participants <p>(a) Evaluation of machine learning model performance on self-reported maternal family history prediction combing structural neuroimaging with mitochondrial haplogroups. (b) Variable importance analysis for top-performing structural neuroimaging and mitochondrial haplogroup models predicting positive self-reported maternal family history.</p> 2026-09-23T17:27:20Z Dataset Dataset 10.1371/journal.page.0000045.t005 https://figshare.com/articles/dataset/_p_a_Evaluation_of_machine_learning_model_performance_on_self-reported_maternal_family_history_prediction_combing_structural_neuroimaging_with_mitochondrial_haplogroups_b_Variable_importance_analysis_for_top-performing_structural_neuroimagi/33975314 CC BY 4.0