2026-10-12T17:11:02Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33973192 2026-09-25T13:50:45Z category_1 category_146 category_7 category_14 category_16 category_21 category_39 category_45 category_734 category_106 portal_87 item_type_3 month_year_09_2026

Long-term stability and blood pressure change tracking with a cuffless wearable device in hypertensive patients Martin Proença (4801410) Pierre-Antonin Rigon (25097302) Guillaume Bonnier (2157910) Damien Ferrario (3816745) Joachim Zahnd (22169617) Mathieu Lemay (330649) Grégoire Wuerzner (541639) Biophysics Space Science Medicine Molecular Biology Physiology Biotechnology Ecology Sociology Biological Sciences not elsewhere classified Science Policy Cuffless blood pressure monitoring hypertension management photoplethysmography PPG calibration stability change tracking Reliable tracking of short- and long-term blood pressure (BP) changes is a prerequisite for clinical adoption of cuffless BP devices. This study evaluated the 6-week stability of BP estimation by CSEM’s wearable photoplethysmography (PPG)-based cuffless BP monitor and its ability to track BP changes in hypertensive patients compared with a validated oscillometric device (Microlife WatchBP Home A). In this feasibility method-comparison study, 30 hypertensive patients attended four visits over 6 weeks. At each visit, BP was estimated as the median of 5-7 consecutive measurements obtained with the cuff-based (Cuff BP) and cuffless (PPG BP) devices. Between-visit systolic and diastolic BP changes (ΔSBP, ΔDBP) were compared between devices. Concordance rate (CR), defined as the percentage of significant BP changes (ΔSBP >15 mmHg, ΔDBP >10 mmHg) showing the same direction with both devices, was also assessed. Thirty participants (18 women; age 54 ± 17 years; BMI 29.2 ± 5.5 kg/m²) were included. Differences between devices were 0.2 ± 12.8 mmHg for ΔSBP and -0.1 ± 7.4 mmHg for ΔDBP. No temporal drift in differences between Cuff ΔBP and PPG ΔBP was observed over 6 weeks. CR for significant BP changes was 83% for SBP and 86% for DBP. CSEM’s wearable cuffless BP monitor provided stable BP estimation and concordant BP tracking during antihypertensive therapy. Interpretation is tempered by substantial variability of the oscillometric reference device. If confirmed in larger studies against a gold-standard reference, these findings could support the clinical acceptance of wearable cuffless BP monitoring. Blood pressure estimation with CSEM’s wearable cuffless device appears to provide stable performance over a 6-week period without needing recalibration.Concordance rates for tracking significant blood pressure changes exceeded 80% between CSEM’s wearable cuffless device and a validated oscillometric cuff device.The high measurement variability observed in oscillometric cuff devices highlights the need for future comparison with the double-blind auscultation gold standard and raises concern regarding the clinical value and interpretability of isolated oscillometric measurements. Blood pressure estimation with CSEM’s wearable cuffless device appears to provide stable performance over a 6-week period without needing recalibration. Concordance rates for tracking significant blood pressure changes exceeded 80% between CSEM’s wearable cuffless device and a validated oscillometric cuff device. The high measurement variability observed in oscillometric cuff devices highlights the need for future comparison with the double-blind auscultation gold standard and raises concern regarding the clinical value and interpretability of isolated oscillometric measurements. 2026-09-25T13:50:45Z Dataset Dataset 10.6084/m9.figshare.33973192.v2 https://figshare.com/articles/dataset/Long-Term_Stability_and_Blood_Pressure_Change_Tracking_with_a_Cuffless_Wearable_Device_in_Hypertensive_Patients/33973192 CC BY 4.0