2026-10-14T20:46:31Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33970879 2026-09-23T05:39:56Z category_7 portal_147 item_type_3 month_year_09_2026

Supplemental Material for: Orbital schwannomatosis –two interesting cases figshare admin karger (2628495) Sumeya Ali Khan (25094271) Tayyab Afghani (9987181) Medicine Medicine <p dir="ltr">Introduction:</p><p dir="ltr">Orbital schwannomas are a rare subtype of peripheral nerve sheath tumors that occur in cranial and peripheral nerves throughout the body.Their location in the orbit accounts for only 1%-4% of all head and neck tumors.Indolent growth delays diagnosis till pressure effects on the delicate neuro-ophthalmic structures within the bony orbit appear. Complete surgical excision is the preferred treatment modality.</p><p dir="ltr">Case reports:</p><p dir="ltr">Our two cases shared the typical clinical picture of long-standing progressive proptosis. However, the intraoperative finding of two discrete, well-encapsulated schwannomas in the same orbit is highly unusual. In both patients, removal of the first lesion did not fully relieve the mass effect, prompting further exploration that revealed a second lesion. Histologically, both lesions were identical, showing the classic biphasic spindle cell pattern with strong S100 positivity. Importantly, neither patient had neurofibromatosis type 1 or 2, excluding syndromic association.</p><p dir="ltr">Conclusion:</p><p dir="ltr">Our cases were diagnosed radiologically to have single intraorbital masses but peroperatively ,two distinct masses were seen.Later ,histologically alike.Such cases are very few in published literature.</p> 2026-09-23T05:39:56Z Dataset Dataset 10.6084/m9.figshare.33970879.v1 https://figshare.com/articles/dataset/Supplemental_Material_for_Orbital_schwannomatosis_two_interesting_cases/33970879 CC BY 4.0