2026-10-07T22:08:05Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33969052 2026-09-22T22:11:29Z category_610 portal_316 item_type_3 month_year_09_2026

Supplementary file 1_Effect of tannic acid content on the properties and antibacterial activity of Shapeable polyvinyl alcohol/sodium alginate/tannic acid/borax (PBST) composite hydrogels.docx Tingxu Xia (22382927) Han Pu (17518191) Mengjue Jin (25092181) Yiyu Wang (9903873) Yuhang Chen (584479) Yuanqing Xu (1676545) Ying Ren (303548) Functional Materials antibacterial activity biocompatibility composite hydrogel one-pot synthesis tannic acid <p>Tannic acid (TA), a natural polyphenol with multiple phenolic hydroxyl groups, is a promising functional component in hydrogel systems. In this study, the role of TA concentration (2, 4, and 8 mg/mL) in polyvinyl alcohol/sodium alginate/tannic acid/borax (PBST) composite hydrogels prepared by a one-pot method was systematically investigated. The shapeability, compressive/rheological properties, swelling, degradation, biocompatibility, and antibacterial activity of the composites were evaluated. Increasing the TA content from 2 to 8 mg/mL raised the compressive modulus from 1.80 to 25.46 kPa, improved rheological performance, and reduced the swelling ratio at 96 h from 67.44% to 29.67% as well as the degradation rate at 21 days from 56.07% to 22.62%, although shapeability decreased at the highest TA level. The hydrogels exhibited favorable in vitro and in vivo biocompatibility. Antibacterial efficacy also increased with TA dosage: the antibacterial rates against Staphylococcus aureus/E. coli were 31.10%/30.01% for PBST0.2, 69.23%/56.75% for PBST0.4, and 79.07%/59.80% for PBST0.8, with the highest TA concentration showing the strongest overall antibacterial effect. The findings suggest that TA is an effective regulator of PBST hydrogel performance, enhancing mechanical and antibacterial properties and being associated with reduced swelling and degradation without obvious loss of biocompatibility. However, the underlying network-related mechanisms remain to be further verified by direct structural characterization in future studies.</p> 2026-09-22T22:11:29Z Dataset Dataset 10.3389/fmats.2026.1873593.s001 https://figshare.com/articles/dataset/Supplementary_file_1_Effect_of_tannic_acid_content_on_the_properties_and_antibacterial_activity_of_Shapeable_polyvinyl_alcohol_sodium_alginate_tannic_acid_borax_PBST_composite_hydrogels_docx/33969052 CC BY 4.0