2026-10-14T00:44:11Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33962185 2026-09-22T05:38:39Z category_658 portal_316 item_type_3 month_year_09_2026

Data Sheet 1_Relationship between change in body composition and cardiorespiratory fitness during cardiac rehabilitation in patients with cardiovascular disease.docx Salaheddin M. Sharif (25087981) Jenna L. Taylor (12415285) Amanda R. Bonikowske (10973304) Thomas P. Olson (3595115) Cell Metabolism CPET DEXA exercise training non-responders responders VO2peak Background<p>Cardiac rehabilitation (CR) improves peak oxygen uptake (VO₂peak) and body composition in patients with cardiovascular disease. However, improvement in VO₂peak is not observed in all patients following a CR program, and whether VO₂peak non-responders also demonstrate limited changes in body composition remains unclear. This study aimed to examine the association between changes in VO₂peak and body composition in patients undergoing a CR program.</p>Methods<p>Retrospective analysis of patients who completed CR between 2015 and 2022 at Mayo Clinic. The study included 143 patients who completed cardiopulmonary exercise testing and dual-energy X-ray absorptiometry pre- and post-CR. Patients were grouped by the change in relative VO₂peak response to CR (responders= Δ>0 vs non-responders=Δ ≤0 mL/kg/min). Two-way repeated ANOVA was used to compare groups, and regression models were used to examine the associations between baseline body composition and changes in body composition with VO₂peak change.</p>Results<p>Among the cohort, 26% were classified as non-responders based on relative VO₂peak measurements. Both groups exhibited a significant improvement in most body composition variables including body fat mass, body fat percentage, body lean percentage, and fat mass index (all p<0.001), with no differences in the percentage of change in body composition variables between groups (p>0.05). Regression models demonstrated that neither baseline body composition nor changes in body composition were significantly associated with changes in VO₂peak.</p>Conclusion<p>Our data suggest that baseline and change in body composition were not significantly associated with changes in VO₂peak in patients undergoing the CR program.</p> 2026-09-22T05:38:39Z Dataset Dataset 10.3389/fendo.2026.1933372.s001 https://figshare.com/articles/dataset/Data_Sheet_1_Relationship_between_change_in_body_composition_and_cardiorespiratory_fitness_during_cardiac_rehabilitation_in_patients_with_cardiovascular_disease_docx/33962185 CC BY 4.0