2026-10-07T19:24:40Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33961594 2026-09-22T04:21:21Z category_374 portal_316 item_type_3 month_year_09_2026

Table 1_A systematic analysis of gut microbiome characteristics in Chinese patients with gestational diabetes mellitus.docx Yukun Wang (1824295) Hui Zheng (58412) Chunyi Yue (24530819) Jinyan Liang (3803014) Xinyu He (447328) Lei Mo (334247) Jian Huang (7250) Xiangyuan Yu (9526894) Clinical and Sports Nutrition association characteristics gestational diabetes mellitus gut microbiota systematic review Objective<p>To systematically analyze the change pattern of core gut microbiota in Chinese gestational diabetes mellitus (GDM) patients and provide basis for GDM early microecological screening and probiotic intervention.</p>Methods<p>Databases including PubMed, web of science, CNKI, and Wanfang were searched to identify reports on the association between gut microbiota and GDM. A quantitative system evaluation was conducted to assess the changes in core gut microbiota levels (such as Bifidobacterium, Lactobacillus, etc.) in GDM.</p>Results<p>Totally, 31 studies involving 6,157 subjects were included. Systematic analysis revealed that levels of Bifidobacterium (SMD = −2.47, 95%CI: −2.86 to −2.09) and Lactobacillus (SMD = −1.82, 95% CI: −2.04 to −1.60) in the GDM were significantly lower than those in controls; while Enterobacteriaceae (SMD = 1.75, 95% CI: 1.53 to 1.98) and Enterococcus (SMD = 1.18, 95%CI: 1.03 to 1.32) were significantly higher than those in non-GDM. Sensitivity analysis shows that the above findings are relatively robust.</p>Conclusion<p>GDM exhibit significant gut microbiota dysbiosis. The reduction in Bifidobacterium and Lactobacillus and the increase in Enterobacteriaceae and Enterococcus may be important micro biological features for the onset and progression of GDM.</p> 2026-09-22T04:21:21Z Dataset Dataset 10.3389/fnut.2026.1902356.s001 https://figshare.com/articles/dataset/Table_1_A_systematic_analysis_of_gut_microbiome_characteristics_in_Chinese_patients_with_gestational_diabetes_mellitus_docx/33961594 CC BY 4.0