2026-10-11T03:00:00Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33957105 2026-09-21T17:40:25Z category_1 category_4 category_7 category_12 category_13 category_14 category_16 category_46 category_734 category_931 category_61 category_64 category_128 category_134 portal_5 item_type_3 month_year_09_2026

<p>Original data analysis.</p> Anzhen Xu (25084500) Yanbo Li (402269) Qing Gong (5369318) Hanrui Sun (23839490) Jiayu Shi (7495841) Jingyu Li (324429) Pengyang Gu (25084503) Jixu Shi (25084506) Xiang Li (114679) Qi Lu (143184) Biophysics Biochemistry Medicine Cell Biology Genetics Molecular Biology Physiology Immunology Biological Sciences not elsewhere classified Information Systems not elsewhere classified Developmental Biology Cancer Hematology Virology vivo validation using uniform manifold approximation suggesting potential crosstalk specific mechanisms underlying protein homeostasis dysregulation omics study provides maladaptive cardiac remodeling intercellular interaction analyses inflammatory signaling pathways dysregulated lactate metabolism diverse condition characterized associated hub gene smooth muscle cells failing control hearts increased hmgn2 expression seven potential lactylation cell rna sequencing cell rna human failing first cell transcription factor significantly upregulated selectively enhanced results indicate resolved map reliable biomarker related genes random forest pseudotime trajectory progressive rise pressure overload mouse model may contribute integrative multi including boruta immune cells identify hmgn2 hmgn2 demonstrating highlights hmgn2 analysis revealed <p>This file contains the raw data and quantitative analysis results for qPCR and histological experiments.</p> <p>(ZIP)</p> 2026-09-21T17:40:15Z Dataset Dataset 10.1371/journal.pone.0357971.s005 https://figshare.com/articles/dataset/_p_Original_data_analysis_p_/33957105 CC BY 4.0