2026-10-13T05:52:05Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33939819 2026-09-18T17:53:35Z category_1 category_915 category_12 category_16 category_24 category_122 portal_5 item_type_3 month_year_09_2026

<p>Energetic parameters of the model (values and ranges are described in Text C, Text E, and Table A in S1 Appendix).</p> Zeno Messi (25073571) Franck Raynaud (5745788) Nathan W. Goehring (20404690) Alexander B. Verkhovsky (25073574) Biophysics Physical Sciences not elsewhere classified Cell Biology Physiology Evolutionary Biology Mental Health sufficiently high levels recent experimental findings initially distributed uniformly adhesion dynamics could simple turnover rules several turnover cycles low turnover rates intermediate turnover rates high turnover rates fundamental emergent behavior xlink "> polarization adhesion drive polarization drive symmetry breaking breaking symmetry solely directional motion emerged anchors hindered motion threshold force required attractive force dipoles minimal model consists elastic cytoskeletal network complex signaling networks simple mechanical network sensitive anchor points symmetry breaking signaling networks network behavior turnover rate anchor points network accumulated elastic bonds mechanical interactions anchor removal traction force dipole force substrate adhesions retraction transitions results demonstrate primarily determined plasma membrane intrinsic property fully understood external cues eventually exceeding balanced contractility <p>Energetic parameters of the model (values and ranges are described in Text C, Text E, and Table A in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1014750#pcbi.1014750.s001" target="_blank">S1 Appendix</a>).</p> 2026-09-18T18:02:25Z Dataset Dataset 10.1371/journal.pcbi.1014750.t001 https://figshare.com/articles/dataset/_p_Energetic_parameters_of_the_model_values_and_ranges_are_described_in_Text_C_Text_E_and_Table_A_in_S1_Appendix_p_/33939819 CC BY 4.0