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        <datestamp>2026-09-18T19:55:58Z</datestamp>
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          <dc:title>BCR_ABL1_CML_Indonesia</dc:title>
          <dc:creator>Djumhana Atmakusumah (597601)</dc:creator>
          <dc:creator>hilman tadjoedin (25029963)</dc:creator>
          <dc:creator>Agus Susanto Kosasih (17299928)</dc:creator>
          <dc:creator>Lyana Setiawan (17299930)</dc:creator>
          <dc:creator>Veronika Juanita Maskito (17299933)</dc:creator>
          <dc:creator>Leovinna Widjaja (25029984)</dc:creator>
          <dc:subject>Haematology</dc:subject>
          <dc:subject>chronic myeloid leukemias</dc:subject>
          <dc:subject>BCR::ABL1 fusion gene</dc:subject>
          <dc:subject>kinase domain mutations</dc:subject>
          <dc:subject>Sanger sequencing approaches</dc:subject>
          <dc:subject>polymerase chain reaction (pcr</dc:subject>
          <dc:description>&lt;p dir="ltr"&gt;This study investigated the spectrum of BCR::ABL1 kinase domain mutations in Indonesian patients with CML treatment resistant. We were gathering target population between July-December 2022, 46 patients fulfilled eligibility criteria and were included in the final analysis. They were assessed using real-time Competitive Allele-Specific TaqMan PCR (RT-CAST PCR) for T315I, however only 32 patients underwent hemi-nested Sanger sequencing for broader analysis. Sokal score, Kaplan Meier analysis, and correlation between survival and mutation were evaluated.&lt;/p&gt;</dc:description>
          <dc:date>2026-09-18T19:55:58Z</dc:date>
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