2026-10-10T01:09:21Z
https://api.figshare.com/v2/oai
oai:figshare.com:article/33867628
2026-09-16T17:53:44Z
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<p>EC<sub>50</sub> values of LOPAC hits protecting against intracellular replication of <i>Burkholderia mallei</i> ATCC 23344<sup>a.</sup></p>
Nichole Orr-Burks (4621435)
Sarah R. Hosking (18981061)
Steven P. Maher (10514444)
Dennis E. Kyle (341177)
Malina A. Bakowski (17941603)
Robert J. Hogan (9524476)
Eric R. Lafontaine (18981082)
Biochemistry
Space Science
Microbiology
Cell Biology
Pharmacology
Biotechnology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Science Policy
Immunology
Biological Sciences not elsewhere classified
Infectious Diseases
throughput screening platform
reproducible endpoint readout
quantifies cytopathic effects
prolonged antimicrobial therapy
key pathogenicity trait
fatal diseases melioidosis
completely protected mice
c mouse model
>- infected monolayers
99 &# 181
facultative intracellular bacteria
vero e6 cells
biological warfare agents
bioactive compounds protecting
day 14 post
800 small molecules
bacterial intracellular replication
burkholderia pseudomallei </
burkholderia mallei </
r </ b
p </ b
l </ b
f </ b
c </ b
disrupt intracellular replication
lethal aerosol infection
intracellular replication
small molecules
burkholderia pseudomallei
burkholderia mallei
burkholderia </
selected compounds
mammalian cells
lethal doses
etiological agents
bacterial leucyl
vivo </
vitro </
bp </
bm </
aerosol infection
</ b
<p>EC<sub>50</sub> values of LOPAC hits protecting against intracellular replication of <i>Burkholderia mallei</i> ATCC 23344<sup>a.</sup></p>
2026-09-16T17:54:19Z
Dataset
Dataset
10.1371/journal.ppat.1014596.t003
https://figshare.com/articles/dataset/_p_EC_sub_50_sub_values_of_LOPAC_hits_protecting_against_intracellular_replication_of_i_Burkholderia_mallei_i_ATCC_23344_sup_a_sup_p_/33867628
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