2026-10-14T15:36:35Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33858472 2026-09-20T14:08:05Z category_24178 category_24811 item_type_3 month_year_09_2026

Source data for “ANXA6 regulates cisplatin resistance in hepatocellular carcinoma through tyrosine metabolism and redox homeostasis” Xiaoxia Xue (24980641) Yan Song (119387) Xuekai Liu (15272978) Jie Zhang (64655) Guowei Liang (25077885) Biochemistry and cell biology not elsewhere classified Oncology and carcinogenesis not elsewhere classified Hepatocellular carcinoma ANXA6 Cisplatin resistance Tyrosine metabolism TAT Redox homeostasis <p dir="ltr">This dataset contains the source data underlying the experimental results and quantitative analyses reported in the associated study investigating the role of ANXA6 in cisplatin resistance in hepatocellular carcinoma (HCC). The deposited data include the individual numerical values used for the quantitative analyses presented in the experimental figures, including cisplatin sensitivity, cell viability, apoptosis, reactive oxygen species (ROS), cell-cycle distribution, RT-qPCR, western blot densitometry, GSH/GSSG, NADPH/NADP+ measurements, and mitochondrial membrane potential analyses. </p><p dir="ltr">The transcriptomic and bioinformatic analyses reported in the associated study were based on publicly available datasets. Bulk transcriptomic data were obtained from the Gene Expression Omnibus (GEO; GSE54175), single-cell RNA-sequencing data were obtained from GEO (GSE290925), and transcriptomic and clinical data were obtained from the TCGA-LIHC cohort. Publicly available immunohistochemical data were obtained from the Human Protein Atlas (HPA). No new bulk RNA-sequencing or single-cell RNA-sequencing data were generated in this study.</p> 2026-09-20T14:08:05Z Dataset Dataset 10.6084/m9.figshare.33858472.v1 https://figshare.com/articles/dataset/Source_data_for_ANXA6_regulates_cisplatin_resistance_in_hepatocellular_carcinoma_through_tyrosine_metabolism_and_redox_homeostasis_/33858472 CC BY 4.0