2026-10-12T00:08:22Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33853564 2026-09-17T11:15:23Z category_27241 item_type_3 month_year_09_2026

Supplementary Material for: Plasma LC-MS/MS Profiling Reveals Distinct Steroidogenic Signatures in Pediatric Adrenocortical Carcinoma and Adenoma Alexandra E Kulle (24961750) Antje Redlich (13258288) Marina Kunstreich (24987516) Ralf Junker (24987536) Stefan Wudy (24987574) Paul-Martin Holterhus (24999024) Michaela Kuhlen (16319058) Other health sciences not elsewhere classified adrenocortical carcinomas adrenocortical adenomas Pediatric Endocrinology LC-MS/MS spectrometry steroid profiling Steroid metabolomics <p dir="ltr">Supplementary figures and tables accompanying the manuscript "Plasma LC-MS/MS Profiling Reveals Distinct Steroidogenic Signatures in Pediatric Adrenocortical Carcinoma and Adenoma" (submitted to The Journal of Clinical Endocrinology & Metabolism, manuscript number jc.2026-01808R1). Includes: Supplementary Figure 1 (heatmap of individual steroid profiles), Supplementary Figure 2 (forest plot of logistic regression estimates), Supplementary Figure 3 (individual steroid concentrations relative to age- and sex-specific upper reference limits), Supplementary Table 1 (proportions of patients above upper reference limits by tumor entity), and Supplementary Table 2 (plasma 17-hydroxypregnenolone concentrations and z-log scores). Data derive from 24 pediatric patients with histologically confirmed adrenocortical tumors (8 adenoma, 15 carcinoma, 1 tumor of indeterminate histology) enrolled in the German MET Registry.</p> 2026-09-17T11:15:23Z Dataset Dataset 10.6084/m9.figshare.33853564.v1 https://figshare.com/articles/dataset/Supplementary_Material_for_Plasma_LC-MS_MS_Profiling_Reveals_Distinct_Steroidogenic_Signatures_in_Pediatric_Adrenocortical_Carcinoma_and_Adenoma/33853564 CC BY 4.0 Open Access after 2027-03-16