2026-10-14T11:09:03Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33847450 2026-09-16T12:40:01Z category_8 portal_316 item_type_3 month_year_09_2026

Supplementary file 1_Utahmycin C, a new glycosylated derivative of a rare azaanthraquinone produced by Streptomyces sp. YD248.docx Fatemeh M. Tajabadi (24981514) Andrew M. Piggott (1335855) Jeff Errington (366288) Yousef Dashti (3876511) Microbiology azaanthraquinone polyketide glycoside streptomyces type II PKS <p>Chemical investigation of Streptomyces sp. YD248 led to the isolation of utahmycin C (1), a new glycosylated member of the rare bacterial 1,3-dimethyl-2-azaanthraquinone family. Its structure was established by NMR spectroscopy and high-resolution mass spectrometry, revealing a β-D-glucuronic acid substituent attached to the azaanthraquinone core. Unusual long-range ⁵J HMBC correlations prompted validation by density functional theory (DFT) through NMR chemical shift calculations, which showed excellent agreement with the experimental data. Bioinformatics analysis identified a biosynthetic gene cluster (BGC) homologous to the reported Erd gene cluster associated with utahmycin A biosynthesis. This study expands the structural diversity of bacterial azaanthraquinones.</p> 2026-09-16T12:40:01Z Dataset Dataset 10.3389/fmicb.2026.1921234.s001 https://figshare.com/articles/dataset/Supplementary_file_1_Utahmycin_C_a_new_glycosylated_derivative_of_a_rare_azaanthraquinone_produced_by_Streptomyces_sp_YD248_docx/33847450 CC BY 4.0