2026-10-12T00:25:53Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33813757 2026-09-15T17:52:50Z category_146 category_272 category_734 category_931 category_69 category_106 category_133 portal_5 item_type_3 month_year_09_2026

<p>Decision-support comparison of imaging-based (in situ hybridization) and sequencing-based (spatial barcoding/capture) spatial transcriptomics approaches. Resolution, coverage, tissue compatibility, availability, and cost are intended as orienting guidance; exact specifications vary by platform and version and should be verified against current vendor or method documentation before selection.</p> Nagomi Kurogi (24949858) Koki Shimbara (24949861) Tatsuya Koreeda (24949864) Koki Tsuyuzaki (6323219) Space Science Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Information Systems not elsewhere classified Inorganic Chemistry Science Policy Plant Biology ten quick tips serial tissue sections review provides biologists leveraging public datasets integrating complementary modalities highlight current limitations g ., merfish et al </ dimensional tissue architecture given biological question g ., visium cell rna sequencing whether st suits div >< p process st data visium hd spanning sequencing data structures biological context study objectives spatial transcriptomics spatial proteomics software tools sharing results reconstructing three neutral roadmap incorporating st foundational work experimental design expanded rapidly enables genome cosmx smi computational tools <p>Decision-support comparison of imaging-based (in situ hybridization) and sequencing-based (spatial barcoding/capture) spatial transcriptomics approaches. Resolution, coverage, tissue compatibility, availability, and cost are intended as orienting guidance; exact specifications vary by platform and version and should be verified against current vendor or method documentation before selection.</p> 2026-09-15T17:52:44Z Dataset Dataset 10.1371/journal.pcbi.1014757.t001 https://figshare.com/articles/dataset/_p_Decision-support_comparison_of_imaging-based_in_situ_hybridization_and_sequencing-based_spatial_barcoding_capture_spatial_transcriptomics_approaches_Resolution_coverage_tissue_compatibility_availability_and_cost_are_intended_as_orienting/33813757 CC BY 4.0