2026-10-06T10:45:59Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33805963 2026-09-15T16:23:51Z portal_1197 item_type_3 month_year_09_2026

Data for Biotinylated photoactive Pt(IV) anticancer complexes Huayun Shi (3928973) Cinzia Imberti (1364502) Huaiyi Huang (1504426) Ian Hands-Portman (1297335) Peter J. Sadler (1297341) Antineoplastic agents Apoptosis Photochemistry Diazines Avidin Irradiation Migrated from ePrints Novel biotinylated diazido-Pt(IV) complexes exhibit high visible light photocytotoxicity while being stable in the dark. Photocytotoxicity and cellular accumulation of all-trans-[Pt(py)2(N3)2(biotin)(OH)] (2a) were enhanced significantly when bound to avidin; irradiation induced dramatic cellular morphological changes in human ovarian cancer cells treated with 2a.<br><br>Data record consists of a rar archive, containing the data, and an accompanying readme file. The 1H NMR and 13C NMR spectra and HR-MS spectra of complexes 2a and 2b are listed in the dataset. More information is listed in the ESI and the accompanying readme file. 2026-09-15T16:23:51Z Dataset Dataset 10.82444/warw.33805963.v1 https://figshare.com/articles/dataset/Data_for_Biotinylated_photoactive_Pt_IV_anticancer_complexes/33805963 CC BY 4.0