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oai:figshare.com:article/33758164 2026-09-14T20:44:47Z portal_1197 item_type_3 month_year_09_2026

Data for Preparation and characterisation of manganese, cobalt and zinc DNA nanoflowers with tuneable morphology, DNA content and size Ysobel R. Baker (7814864) Jinfeng Chen (118034) Jason Brown (253739) Afaf H. El-Sagheer (1666675) Philip Wiseman (24900985) Errin Johnson (4843575) Paul Goddard (564595) Tom Brown (9263) DNA polymerases Nanocrystals Nucleic acids Migrated from ePrints Recently reported DNA nanoflowers are an interesting class of organic-inorganic hybrid materials which are prepared using DNA polymerases. DNA nanoflowers combine the high surface area and scaffolding of inorganic Mg2P2O7 nanocrystals with the targeting properties of DNA, whilst adding enzymatic stability and enhanced cellular uptake. We have investigated conditions for chemically modifying the inorganic core of these nanoflowers through substitution of Mg2+ with Mn2+, Co2+ or Zn2+ and have characterised the resulting particles. These have a range of novel nanoarchitectures, retain the enzymatic stability of their magnesium counterparts and the Co2+ and Mn2+ DNA nanoflowers have added magnetic properties. We investigate conditions to control different morphologies, DNA content, hybridisation properties, and size. Additionally, we show that DNA nanoflower production is not limited to Ф29 DNA polymerase and that the choice of polymerase can influence the DNA length within the constructs. We anticipate that the added control of structure, size and chemistry will enhance future applications.<br><br>Data record consists of a zip archive containing the data files in .dat format and a readme file. Data files are named according to the corresponding figure in the related paper. Further information on specific data files can be found in the attached readme file. 2018-06-21T00:00:00Z Dataset Dataset 10.82444/warw.33758164.v1 https://figshare.com/articles/dataset/Data_for_Preparation_and_characterisation_of_manganese_cobalt_and_zinc_DNA_nanoflowers_with_tuneable_morphology_DNA_content_and_size/33758164 CC BY 4.0