2026-10-10T07:42:57Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33756250 2026-09-14T20:09:46Z portal_1197 item_type_3 month_year_09_2026

Data for Millennia of genomic stability within the invasive Para C Lineage of Salmonella enterica: Concoct 4 Zhemin Zhou (157214) Inge Lundstrøm (24893668) Alicia Tran Dien (24899239) Sebastián Duchêne (110910) Nabil-Fareed Alikhan (5066198) Martin J. Sergeant (24732832) Gemma Langridge (3549053) Anna K. Fotakis (4066471) Satheesh Nair (157213) Hans K. Stenøien (8811296) Stian S. Hamre (24893671) Sherwood Casjens (55674) Christopher Quince (178494) Axel Christophersen (9257291) Nicholas R. Thomson (6811496) François-Xavier Weill (157212) Simon Ho (787728) M. Thomas P. Gilbert (7247759) Mark Achtman (126786) Typhoid fever -- Genetic aspects -- History Typhoid fever -- Trondheim (Norway) -- 13th century Migrated from ePrints Salmonella enterica serovar Paratyphi C is the causative agent of enteric (paratyphoid) fever. While today a potentially lethal infection of humans that occurs in Africa and Asia, early 20th century observations in Eastern Europe suggest it may once have had a wider-ranging impact on human societies. We recovered a draft Paratyphi C genome from the 800-year-old skeleton of a young woman in Trondheim, Norway, who likely died of enteric fever. Analysis of this genome against a new, significantly expanded database of related modern genomes demonstrated that Paratyphi C is descended from the ancestors of swine pathogens, serovars Choleraesuis and Typhisuis, together forming the Para C Lineage. Our results indicate that Paratyphi C has been a pathogen of humans for at least 1,000 years, and may have evolved after zoonotic transfer from swine during the Neolithic period.<br><br>Single-stranded deamination rates for Ragna, human DNA and 11 MAGs 2018-05-04T00:00:00Z Dataset Dataset 10.82444/warw.33756250.v1 https://figshare.com/articles/dataset/Data_for_Millennia_of_genomic_stability_within_the_invasive_Para_C_Lineage_of_Salmonella_enterica_Concoct_4/33756250 CC BY 4.0