2026-10-08T15:23:40Z
https://api.figshare.com/v2/oai
oai:figshare.com:article/33729700
2026-09-16T12:36:37Z
category_24733
category_24859
item_type_3
month_year_09_2026
Supporting data and materials for the systematic review and meta-analysis of extracellular vesicles as nanocarriers for therapeutic agent delivery in ischemic stroke
Ruixin Li (24867967)
Shuangshuang Li (24876060)
Yingming Liu (24876062)
Pengyu Wang (24876068)
Yuanhao Chen (24876129)
Yan Feng (24876139)
Baofeng Xu (24876165)
Hanyu Ren (24876499)
Chengyun Li (369037)
Central nervous system
Pharmaceutical delivery technologies
extracellular vesicles
ischemic stroke
nanocarriers
drug delivery
meta-analysis
<p dir="ltr">This repository contains the supporting data and materials for the systematic review and meta-analysis entitled: "Extracellular Vesicles as Nanocarriers for Therapeutic Agent Delivery in Ischemic Stroke: A Systematic Review and Meta-Analysis of Animal Studies".</p><p dir="ltr">The repository includes the extracted quantitative data used for meta-analyses and the risk-of-bias assessment data from preclinical studies comparing therapeutic agent-loaded extracellular vesicles (EVs) with corresponding free therapeutic agents in animal models of ischemic stroke. The datasets include information used for analyses of infarct volume, neurological outcomes, brain accumulation of therapeutic agents, and additional comparisons between engineered therapeutic agent-loaded EVs and unmodified therapeutic agent-loaded EVs. Risk-of-bias assessments were performed using the SYRCLE risk-of-bias tool.</p><p dir="ltr">The completed PRISMA 2020 Checklist for this systematic review is also included in this repository. All data were extracted from published studies included in this systematic review. Quantitative analyses were performed using Review Manager (RevMan) version 5.4 and Stata version 17.0.</p>
2026-09-16T12:36:37Z
Dataset
Dataset
10.6084/m9.figshare.33729700.v3
https://figshare.com/articles/dataset/Data_supporting_the_systematic_review_and_meta-analysis_of_extracellular_vesicles_as_nanocarriers_for_therapeutic_agent_delivery_in_ischemic_stroke/33729700
CC BY 4.0