2026-10-13T19:09:19Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33728214 2026-09-14T10:04:56Z category_4 category_12 category_13 category_19 category_272 category_873 portal_63 item_type_3 month_year_09_2026

Synthesis of Rhodium and Ruthenium Pi-Complexes with Pendant Amide Substituents for Intramolecular Proton Transfer upon Activation of C–H Bonds Tatiana N. Petrushina (24643377) Alevtina S. Voskresenskaia (24874758) Roman A. Pototskiy (24874761) Yulia V. Nelyubina (563717) Dmitry S. Perekalin (2412760) Biochemistry Cell Biology Genetics Pharmacology Environmental Sciences not elsewhere classified Chemical Sciences not elsewhere classified pendant amide substituents pendant amide groups internal proton acceptors >- methoxy -< 6 </ sub 5 </ sub 2 </ sub 4 </ sub p </ n </ >- methylbenzamide ruthenium pi methyl oxime metal chlorides major product isocoumarin instead expected isoquinolone corresponding dienes [( c Cyclopentadienyl and arene complexes with pendant amide substituents [(C₅Me₄CH₂CH₂NHR)RhCl₂]<i>_n</i> and [(C₆H₅CH₂CH₂NHR)RuCl₂]<i>_n</i> (R = COCF₃, Ts) were synthesized by heating the corresponding dienes with metal chlorides. They were tested as catalysts for the annulation of <i>N</i>-methoxy-<i>p</i>-methylbenzamide with alkynes. Contrary to our expectations, the pendant amide groups did not act as internal proton acceptors and did not accelerate the C–H activation process. However, it was found that the reaction of <i>N</i>-methoxy-<i>p</i>-methylbenzamide with 4-octyne in the presence of various rhodium complexes produced an O-methyl oxime of isocoumarin instead of the expected isoquinolone as the major product. 2026-09-14T00:00:00Z Dataset Dataset 10.1021/acs.organomet.6c00236.s001 https://figshare.com/articles/dataset/Synthesis_of_Rhodium_and_Ruthenium_Pi-Complexes_with_Pendant_Amide_Substituents_for_Intramolecular_Proton_Transfer_upon_Activation_of_C_H_Bonds/33728214 CC BY-NC 4.0