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        <identifier>oai:figshare.com:article/33667694</identifier>
        <datestamp>2026-09-12T12:24:19Z</datestamp>
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          <dc:title>Evaluation of a 0.05 T low-field MRI system for canine brain imaging via comparison with images acquired at 1.5 T field strength: a pilot cadaver study</dc:title>
          <dc:creator>Elisabeth Maria Burgers (24391406)</dc:creator>
          <dc:creator>Samantha Miles (21755583)</dc:creator>
          <dc:creator>Stefanie Veraa (24391415)</dc:creator>
          <dc:creator>Thomas O'Reilly (651385)</dc:creator>
          <dc:creator>Ruben van den Broek (24391409)</dc:creator>
          <dc:creator>Chloé Najac (10650668)</dc:creator>
          <dc:creator>Beatrice Lena (11781076)</dc:creator>
          <dc:creator>Andrew Webb (464690)</dc:creator>
          <dc:subject>Space Science</dc:subject>
          <dc:subject>Physical Sciences not elsewhere classified</dc:subject>
          <dc:subject>Medicine</dc:subject>
          <dc:subject>Cell Biology</dc:subject>
          <dc:subject>Neuroscience</dc:subject>
          <dc:subject>Physiology</dc:subject>
          <dc:subject>Biological Sciences not elsewhere classified</dc:subject>
          <dc:subject>Canine neuroimaging</dc:subject>
          <dc:subject>low field magnetic resonance imaging</dc:subject>
          <dc:subject>image contrast</dc:subject>
          <dc:subject>hydrocephalus</dc:subject>
          <dc:subject>one health</dc:subject>
          <dc:subject>sustainable imaging</dc:subject>
          <dc:subject>permanent magnets</dc:subject>
          <dc:subject>Halbach array</dc:subject>
          <dc:description>&lt;p&gt;Magnetic resonance imaging (MRI) systems continue to grow in number in veterinary and human medicine with higher field strength magnets increasingly available; however, the associated high costs have created healthcare inequities. This technical feasibility study aimed to evaluate a low-cost, portable, and permanent magnet-based 0.05 T low-field system (LF), originally designed for human neuroimaging, for assessing the canine brain. By using 23 canine cadavers, a scanning protocol was developed, consisting of transverse T1-weighted (T1w) and T2-weighted (T2w) sequences, and compared to a 1.5 T (HF) protocol for the visibility of 22 anatomical features. For the purpose of hydrocephalus evaluation, the LF system showed non-inferior detection of the lateral ventricles (LV) and mesencephalic aqueduct on T2w sequences with &gt;90% conditional probability for detecting these features on the LF, given they were present on the HF. For T1w sequences, the LF system had inconclusive non-inferiority for detection of LV with 76.6% conditional probability. In summary, a canine brain scanning protocol was successfully developed for a 0.05 T MRI with preliminary evaluation suggestive that this device can aid with the detection of hydrocephalus. Future &lt;i&gt;in vivo&lt;/i&gt; studies are required to evaluate the device's true clinical application.&lt;/p&gt;</dc:description>
          <dc:date>2026-09-12T12:24:19Z</dc:date>
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          <dc:identifier>10.6084/m9.figshare.33667694.v1</dc:identifier>
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          <dc:rights>CC BY 4.0</dc:rights>
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