2026-10-12T09:36:25Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33568933 2026-09-14T20:46:37Z category_24706 item_type_3 month_year_09_2026

Raw dataset: Molecular epidemiology of extraintestinal pathogenic Escherichia coli causing bloodstream infections in hospitalised patients in the healthcare sectors in Gauteng, South Africa Lizzy Madiwani (24702526) Medical microbiology not elsewhere classified Extraintestinal pathogenic E. coli antimicrobial resistance sequence types bloodstream infections high-risk clones whole genome sequencing Gauteng This study investigated the molecular epidemiology of extraintestinal pathogenic Escherichia coli (ExPEC) causing bloodstream infections (BSIs) in hospitalised patients in Gauteng, South Africa. A total of 466 E. coli isolates collected from public and private healthcare facilities between 2021 and 2022 were analysed.The study characterised ST131 and non-ST131 E. coli isolates using PCR-based methods, including ST131 clade and subclade assignment, 7-SNP-qPCR clonotyping and multiplex PCR for major sequence types. Antimicrobial susceptibility testing and assessment of extended-spectrum beta-lactamase (ESBL) production were also performed. Selected non-ST131 isolates underwent whole genome sequencing to investigate sequence types, antimicrobial resistance genes, virulence genes, plasmid content and genetic relatedness.The dataset contains the laboratory, antimicrobial susceptibility and molecular characterisation data generated during the study and provides data for investigating ExPEC lineages, antimicrobial resistance and molecular epidemiology in healthcare settings in Gauteng, South Africa. 2026-09-14T20:46:37Z Dataset Dataset 10.6084/m9.figshare.33568933.v1 https://figshare.com/articles/dataset/Raw_dataset_Molecular_epidemiology_of_extraintestinal_pathogenic_Escherichia_coli_causing_bloodstream_infections_in_hospitalised_patients_in_the_healthcare_sectors_in_Gauteng_South_Africa/33568933 CC BY 4.0