2026-10-09T02:46:14Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33413509 2026-09-30T08:45:44Z category_24271 category_27046 category_27049 category_24892 item_type_3 month_year_09_2026

Additional files: Manuscript titled "<b>Haplotype diversity and variant switching associated with long-term transmission and outbreak dynamics of Dengue virus 3 genotype III lineages</b>" Rou Xuan Lee (15955350) Gladys Yeo (113330) Carmen Koo (5615159) Vanessa Goh (24693178) Yee Ling Lai (10035791) Judith Chui Ching Wong (10035800) Lee Ching Ng (9311385) Hapuarachchige Chanditha Hapuarachchi (9264182) Phylogeny and comparative analysis Disease surveillance Environmental epidemiology Other biomedical and clinical sciences not elsewhere classified phylogeny of viruses genomic surveillance data haplotype association study Molecular Epidemiology Large-scale vector surveillance indices <p dir="ltr">Despite improvements in genomic surveillance coverage in dengue endemic settings, there is limited literature on the long-term evolutionary dynamics of DENV lineages that contribute to epidemics in hyperendemic settings. The present study aimed to address this knowledge gap by analysing serially collected DENV genomic surveillance data in Singapore, where DENV populations have closely been monitored since 2006 to facilitate outbreak risk assessment. The study investigated the long-term temporal dynamics of two DENV-3 genotype III lineages associated with two outbreaks in Singapore during 2019-2022. We hypothesized that the two lineages differ in intra-lineage haplotype composition, substitution patterns and temporal dynamics, and that overall diversity scales in parallel to transmission intensity.</p> 2026-09-30T08:45:44Z Dataset Dataset 10.6084/m9.figshare.33413509.v3 https://figshare.com/articles/dataset/Additional_files_Manuscript_titled_b_Haplotype_diversity_and_variant_switching_associated_with_long-term_transmission_and_outbreak_dynamics_of_Dengue_virus_3_genotype_III_lineages_b_/33413509 CC BY 4.0