2026-10-13T10:08:48Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33407803 2026-09-21T14:45:01Z category_24193 category_24208 category_24310 category_24307 category_24298 category_24295 portal_918 item_type_3 month_year_09_2026

Chapter 3 Supplementary Tables. 3.3.1 - 3.4.3 Jake Butler (24511640) Genomics and transcriptomics Bioinformatics and computational biology not elsewhere classified Genomics Genome structure and regulation Gene expression (incl. microarray and other genome-wide approaches) Epigenetics (incl. genome methylation and epigenomics) Osteoarthritis Functional Genomics ATAC-seq Hi-C CUT&RUN RNA-seq Chondrocytes Quality Control <p dir="ltr"><b>Supplementary Tables for: Presentation of Matched Epigenomic and Transcriptomic Maps Derived from Primary Chondrocytes</b></p><p dir="ltr">This Excel workbook contains the supplementary tables supporting Chapter 3, <i>Presentation of Matched Epigenomic and Transcriptomic Maps Derived from Primary Chondrocytes</i>. The tables provide the complete metadata, quality-control metrics, benchmarking datasets, and analytical outputs underpinning the generation and validation of a comprehensive multi-omic resource comprising ATAC-seq, CUT&RUN, Hi-C and RNA-seq data from primary osteoarthritis (OA) chondrocytes isolated from matched intact and degraded cartilage.</p><p dir="ltr">The supplementary tables document the quality assessment, biological validation, and reference-based comparisons used to establish the robustness and biological relevance of the generated molecular maps. These resources support the creation of disease-relevant chromatin accessibility, histone modification, chromatin conformation, and transcriptomic datasets for downstream investigation of osteoarthritis regulatory mechanisms and functional interpretation of genetic risk loci.</p> 2026-09-21T14:45:01Z Dataset Dataset 10.48420/33407803.v1 https://figshare.com/articles/dataset/Chapter_3_Supplementary_Tables_3_3_1_-_3_4_3/33407803 CC BY 4.0 Open Access after 2028-09-01