2026-10-13T09:44:55Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33394369 2026-09-12T09:27:34Z category_24853 category_24523 item_type_3 month_year_09_2026

Replication Data and R Code for “Effectiveness and Safety of Intra-Articular Hyaluronic Acid Conjugated with Fibrinogen in Knee Osteoarthritis: A Prospective Single-Arm Study kim xoa cao (24679405) nam anh tang ha (24679440) loi do van (24679442) phong le dang (24679445) mai anh tang ha (24679450) hung tran manh (24679452) Clinical pharmacology and therapeutics Orthopaedics Knee osteoarthritis Hyaluronic acid Fibrinogen Intra-articular injection Biplanar EOS imaging Patient-reported outcomes <p dir="ltr">This dataset accompanies the study entitled “Effectiveness and Safety of Intra-Articular Hyaluronic Acid conjugated with Fibrinogen in Knee Osteoarthritis: A Prospective Single-Arm Study.”</p><p dir="ltr">The dataset contains data from 31 patients with symptomatic knee osteoarthritis who received a single intra-articular injection of conjugated hyaluronic acid and fibrinogen and completed 12 months of follow-up. Clinical outcomes were assessed at baseline, 2 weeks, 1 month, 3 months, 6 months, and 12 months, including Visual Analog Scale (VAS) pain scores at rest and during movement, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Lysholm Knee Score, and SF-36 physical and mental component scores.</p><p dir="ltr">The dataset also includes baseline demographic and clinical characteristics and biomechanical parameters obtained from standing biplanar EOS imaging. These data were used to evaluate the effectiveness and safety of intra-articular hyaluronic acid combined with fibrinogen in patients with mild-to-moderate knee osteoarthritis.</p><p dir="ltr">The accompanying README file provides descriptions of the variables and guidance for interpreting the dataset.</p><p dir="ltr"><b>Clinical trial registration:</b> ClinicalTrials.gov, NCT07323342.</p> 2026-09-12T09:27:34Z Dataset Dataset 10.6084/m9.figshare.33394369.v4 https://figshare.com/articles/dataset/Replication_Data_and_R_Code_for_Effectiveness_and_Safety_of_Intra-Articular_Hyaluronic_Acid_Combined_with_Fibrinogen_in_Knee_Osteoarthritis_A_Prospective_Single-Arm_Study/33394369 CC BY 4.0