2026-10-09T19:53:38Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33394090 2026-09-23T03:54:56Z category_24139 portal_886 item_type_3 month_year_09_2026

Supporting data for “Role of SH3 domain binding kinase (SBK1) in stress granule (SG) dynamics” Yaowen Hai (16479564) Cell development, proliferation and death stress granules assembly SBK1 HCC progression <p dir="ltr">In this study, we confirmed that the expression of SG core proteins was upregulated during the cSG induction phase, such as in fasted Huh7 cells and C57 mouse liver. Even though total G3BP1 protein levels remained unaffected, this indicates a severe translation arrest during SG formation. Moreover, the effect of SBK1 in regulating SG dynamics can be ascribed to its capacity to enhance the dimerization of G3BP1, as dimerized G3BP1 increased in HEK293 cells upon SBK1 overexpression.</p> 2026-09-23T03:54:56Z Dataset Dataset 10.25442/hku.33394090.v1 https://figshare.com/articles/dataset/Supporting_data_for_Role_of_SH3_domain_binding_kinase_SBK1_in_stress_granule_SG_dynamics_/33394090 CC BY-NC 4.0 Open Access after 2030-08-31