2026-10-14T08:16:21Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33359493 2026-10-03T16:58:23Z category_24367 category_24205 category_24178 item_type_3 month_year_10_2026

Additional supplementary materials for “Mapping the Functional Landscape and Viral Diversity of 2A Peptides” Adesh Baral (24662948) Aditi Kothiala (24663376) Kevin Xu Zhong (16470363) Janelle Cheung (21225209) Stephane Flibotte (11269626) Simcha Srebnik (24663388) Khanh Dao Duc (21015305) Curtis Suttle (508501) Eric Jan (24662951) Virology Translational and applied bioinformatics Biochemistry and cell biology not elsewhere classified Ribosome tRNA Translation 2A peptide Peptidyl-tRNA hydrolysis 2A peptide-mediated StopGo translational recoding RNA virus Reverse-transcribing element <h3 dir="ltr"><b>Description</b></h3><p dir="ltr">Here, we provide supplementary materials for the article, entitled “<i>Mapping the Functional Landscape and Viral Diversity of 2A Peptides</i>”, available as a preprint on bioRxiv: <a href="https://www.biorxiv.org/content/10.64898/2026.09.24.754024v1?utm_source=chatgpt.com" target="_blank">https://www.biorxiv.org/content/10.64898/2026.09.24.754024v1</a>.</p><p><br></p><h3 dir="ltr"><b>Related resources</b></h3><p dir="ltr">The phylogenetic trees of RdRp sequences (Fig. 6) and 2A-peptide sequences (Fig. S6) are also available through the publicly accessible iTOL project: <a href="https://itol.embl.de/shared/xuzhong1" target="_blank" rel="noreferrer">https://itol.embl.de/shared/xuzhong1</a>.</p><ul><li>RdRp tree (Fig. 6): <a href="https://itol.embl.de/tree/12818921023421441790365971" target="_blank" rel="noreferrer">https://itol.embl.de/tree/12818921023421441790365971</a>.</li><li>2A-peptide tree (Fig. S6): <a href="https://itol.embl.de/tree/12818921023425171790365987" target="_blank" rel="noreferrer">https://itol.embl.de/tree/12818921023425171790365987</a>.</li></ul><p dir="ltr"><br></p><p dir="ltr">Additional code could be found in GitHub via this link: <a href="https://github.com/kevinzhongxu/RTEs_classifier" target="_blank" rel="noreferrer">https://github.com/kevinzhongxu/RTEs_classifier</a>.</p><p dir="ltr"><br></p><h3 dir="ltr"><b>References</b></h3><ol><li>Baral A, Kothiala A, Zhong KX, Cheung J, Flibotte S, Srebnik S, Dao Duc K, Suttle CA, and Jan E. (2026) Mapping the Functional Landscape and Viral Diversity of 2A Peptides. bioRxiv. DOI: <a href="https://www.biorxiv.org/content/10.64898/2026.09.24.754024v1" target="_blank" rel="noreferrer">10.64898/2026.09.24.754024</a>.</li><li>Baral A, Kothiala A, Zhong KX, Cheung J, Flibotte S, Srebnik S, Dao Duc K, Suttle CA, and Jan E. (2026) Mapping the Functional Landscape and Viral Diversity of 2A Peptides. ********, **<b>(##</b><b>):******</b>. DOI: ********. PMCID: ********. PMID: ********.</li></ol><p><br></p> 2026-10-03T16:58:23Z Dataset Dataset 10.6084/m9.figshare.33359493.v3 https://figshare.com/articles/dataset/Additional_supplementary_materials_for_Functional_landscape_of_2A_peptides_mediating_peptidyl-tRNA_hydrolysis_via_high-throughput_mutagenesis_and_viral_mining_/33359493 CC BY 4.0