2026-10-14T12:12:19Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33322644 2026-09-22T06:55:19Z category_24787 category_24502 category_24625 portal_886 item_type_3 month_year_09_2026

Supporting data for “Wild-Type RAS Promotes Pulmonary Metastasis in Human Hepatocellular Carcinoma: Mechanistic Insights and a Natural Compound-Based Therapeutic Strategy” Zixin Feng (13275045) Cancer therapy (excl. chemotherapy and radiation therapy) Gastroenterology and hepatology Innate immunity Wild-type RAS Hepatocellular Carcinoma Pulmonary metastasis Immune evasion Exosome Berberine (BBR) <p dir="ltr">This dataset comprises all raw and processed experimental data generated from a doctoral research project investigating the mechanistic role of wild‑type RAS in promoting pulmonary metastasis in hepatocellular carcinoma (HCC) and evaluating berberine (BBR) as a natural compound‑based therapeutic strategy. The data are organised into seven subfolders, corresponding to Chapters 1‑7 of the associated thesis, to facilitate navigation and reproducibility.</p><p dir="ltr"> Each chapter folder contains the following types of files: (1) high‑resolution TIFF images of all figures presented in the corresponding chapter; (2) GraphPad Prism files containing raw numerical data, statistical analyses, and publication‑ready graphs for all quantitative experiments; and (3) Excel spreadsheets containing clinical data from the human HCC tissue microarray cohort, including de‑identified clinicopathological parameters, survival outcomes, and multiplex immunofluorescence expression scores.</p><p dir="ltr"> All raw data have been processed, normalised, and statistically analysed using appropriate methods as detailed in the thesis. The dataset contains no personally identifiable information; all patient data are fully anonymised. Animal experimental data were obtained under ethical approval (CULATR, The University of Hong Kong).</p><p><br></p> 2026-09-22T06:55:19Z Dataset Dataset 10.25442/hku.33322644.v1 https://figshare.com/articles/dataset/Supporting_data_for_Wild-Type_RAS_Promotes_Pulmonary_Metastasis_in_Human_Hepatocellular_Carcinoma_Mechanistic_Insights_and_a_Natural_Compound-Based_Therapeutic_Strategy_/33322644 CC BY-NC 4.0 Embargoed