2026-10-07T00:27:17Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33292902 2026-09-21T09:25:21Z category_24169 category_24178 category_24139 category_24151 portal_886 item_type_3 month_year_09_2026

Supporting data for “Inhibition of Replication Licensing Using Small Molecular Inhibitors” Wenxiong Wu (19202827) Structural biology (incl. macromolecular modelling) Biochemistry and cell biology not elsewhere classified Cell development, proliferation and death Enzymes DNA replication licensing factors Replication initiation Origin recognition complex MCM2-7 helicase RL5a Ciprofloxacin Cryo-electron microscopy DNA-encoded library Cancer therapeutics <p dir="ltr">Dataset submitted in fulfillment of the requirements for the Degree of MPhil at The University of Hong Kong. The file contains figure panels, figure legends, and associated experimental summaries related to the thesis entitled "Inhibition of Replication Licensing Using Small Molecular Inhibitors". The dataset covers research on small-molecule inhibition of replication licensing factors, including RL5a-mediated inhibition of human ORC, CPFX-mediated effects on MCM2-7 helicase, and construct preparation for DNA-encoded library-based inhibitor discovery.</p><p><br></p> 2026-09-21T09:25:21Z Dataset Dataset 10.25442/hku.33292902.v1 https://figshare.com/articles/dataset/Supporting_data_for_Inhibition_of_Replication_Licensing_Using_Small_Molecular_Inhibitors_/33292902 CC BY-NC 4.0 Open Access after 2027-08-21