2026-10-09T13:18:54Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33221934 2026-09-21T01:33:43Z category_24799 category_25207 category_24787 category_25075 portal_886 item_type_3 month_year_09_2026

Supporting data for "Antitumor agrimol B and derivatives as respiratory complex II inhibitors targeting multiple mitochondrial and endoplasmic reticulum-Golgi vulnerabilities" Hanyue Xiao (11269815) Molecular targets Natural products and bioactive compounds Cancer therapy (excl. chemotherapy and radiation therapy) Bioassays Natural products analogues anticancer activity experiments molecular target identification <p dir="ltr">Dataset includes total four files which corresponding to four chapters (Chapter 2-5) in the thesis. </p><p dir="ltr">Includes fluorescence images, immunoblots images, various biological cellular assays images, NanoSIMS images, antiangiogenetic assay images, cell invasion images, wound-healing images, and LCMS images in jpeg/tif format, easily readable. Includes cryo-EM images in tif fromat and done through Chimera X software, easily readable. </p><p dir="ltr">Includes PDO data report in pdf format, easily readable. And includes xlsx. sheets of high content live and dead cell assay done through MetaXpress analysis software; xlsx. sheets of quantitative proteomic and RNA-Seq data were analyzed through R studio; xlsx. sheets of cell viability assay, high content analysis (TMRM and MTG staining) done through ImageJ/Figi software; xlsx. sheets of mitochondrial matrix pH measurement done through Nikon analysis software; xlsx. sheets of ROS measurement done through FlowJo software; and xlsx. sheets of bioinformatic analysis were downloaded form CEPIA platform.</p> 2026-09-21T01:33:43Z Dataset Dataset 10.25442/hku.33221934.v1 https://figshare.com/articles/dataset/Supporting_data_for_Antitumor_agrimol_B_and_derivatives_as_respiratory_complex_II_inhibitors_targeting_multiple_mitochondrial_and_endoplasmic_reticulum-Golgi_vulnerabilities_/33221934 CC BY-NC 4.0 Open Access after 2029-12-31