2026-10-06T08:17:53Z https://api.figshare.com/v2/oai

oai:figshare.com:article/33191637 2026-10-01T12:42:47Z category_24226 category_23962 item_type_3 month_year_10_2026

Data and code for metabolic decompensation under co-occurring thermal-hypoxic stress in Pacific oysters Chao Guo (13221231) Marine and estuarine ecology (incl. marine ichthyology) Aquaculture Pacific oyster thermal hypoxia RNA-seq ATAC-seq alternative splicing ESRRA ocean warming coastal deoxygenation <p dir="ltr">Processed data and analysis workflows supporting the study “Metabolic decompensation under co-occurring thermal-hypoxic stress: ESRRA alternative splicing drives non-additive oyster responses to coastal compound climate stress.” The package includes environmental temperature, salinity, and dissolved-oxygen data for oyster-associated shallow habitats (1995–2025), RNA-seq and ATAC-seq matrices from Pacific oyster gill tissues, sample metadata, peak annotations, survival-analysis code, RNA-seq and ATAC-seq workflow documentation, RNA–ATAC integration instructions, and ESRRA structural-modeling and molecular-docking workflows. Treatment groups are normoxic control (C), heat (H), hypoxia (L), and combined heat–hypoxia (HL). RNA-seq includes 39 libraries sampled at baseline and 6, 24, 48, and 72 h; ATAC-seq includes one control library and six 48-h libraries. Raw sequencing data are available from NCBI SRA under PRJNA1509994. The processed matrices and workflow files are provided for reuse and reproducibility.</p> 2026-10-01T12:42:47Z Dataset Dataset 10.6084/m9.figshare.33191637.v4 https://figshare.com/articles/dataset/Data_and_code_for_metabolic_decompensation_under_co-occurring_thermal-hypoxic_stress_in_Pacific_oysters/33191637 CC BY 4.0 Open Access after 2027-08-09