2026-09-19T12:14:15Z https://api.figshare.com/v2/oai

oai:figshare.com:article/32995337 2026-05-01T00:00:00Z portal_693 item_type_8 month_year_05_2026

Bioinspired Mo/W-Oxo Complexes: Synthesis and Reactivity Across Multiple Ligand Scaffolds - Ira (24400283) Chemistry Inorganic Selective C–H bond functionalization remains a major challenge in synthetic chemistry, while molybdenum and tungsten-containing enzymes carry out difficult oxidative transformations with remarkable efficiency and selectivity under mild conditions. Among these, the xanthine oxidoreductase family provides an important model for understanding how high-valent metal-oxo centers and sulfur- rich ligand environments work together to control structure and reactivity. Molybdenum and tungsten complexes were investigated as bioinspired models of these active sites, with particular focus on ligand platforms designed to capture key structural features of the enzymatic coordination environment. The study focuses on how metal identity and ligand environment shape oxo stability, electronic structure, and reactivity, especially in systems where the strong tungsten-oxo bond restricts chemical transformation. Together, these studies provide insight into the structural and chemical factors that govern Mo/W oxo reactivity and contribute to the broader design of functional biomimetic systems for oxidation chemistry. 2026-05-01T00:00:00Z Text Thesis 10.25417/uic.32995337.v1 https://figshare.com/articles/thesis/Bioinspired_Mo_W-Oxo_Complexes_Synthesis_and_Reactivity_Across_Multiple_Ligand_Scaffolds/32995337 In Copyright Open Access after 2028-05-01