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oai:figshare.com:article/32805299 2026-10-01T16:16:44Z portal_1172 item_type_8 month_year_10_2026

Understanding the cognitive and psychosocial impact of anti-NMDA receptor encephalitis Laura Burke (106805) PUREID: 671086919 Anti-N-Methyl-D-Aspartate Receptor Encephalitis patient reported outcome measures quality of Life psychological well-being neuropsychology cognitive ability <p>This thesis aims to contribute to the growing evidence base examining the long-term cognitive and psychosocial outcomes of anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDARE). Despite increasing recognition of the condition, understanding of long-term neurocognitive outcomes following diagnosis remains variable across existing studies. In addition, the long-term impact of anti-NMDARE on psychological wellbeing, quality of life (QOL), and everyday functioning is poorly understood.</p><p></p><p></p><p>The first paper comprised a scoping review that mapped existing evidence on patient-reported QOL and psychological functioning (i.e. anxiety and depression), alongside an appraisal of methodological quality. The second paper presented a cross-sectional case series employing a convergent parallel mixed methods design. Five participants with a confirmed diagnosis completed a series of cognitive tasks and psychosocial outcome measures, alongside a semi-structured interview which explored the challenges faced and supports required post-diagnosis.</p><br><i>Thesis is embargoed until 31 July 2029.</i><br> 2026-10-01T16:16:44Z Text Thesis 10.17034/32805299.v1 https://figshare.com/articles/thesis/Understanding_the_cognitive_and_psychosocial_impact_of_anti-NMDA_receptor_encephalitis/32805299 All Rights Reserved Open Access after 2029-07-31