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oai:figshare.com:article/32637846 2026-10-01T16:48:27Z portal_1172 item_type_8 month_year_10_2026

Bioinformatic and genomic analyses to identify mitochondrial genomic features associated with chronic kidney disease Ruaidhrí Cappa (24167859) PUREID: 512991547 Chronic kidney disease renal disease GWAS EWAS mitochondrial genomics bioinformatics statistics Chronic kidney disease (CKD) is responsible for considerable morbidity and mortality and lacks a specific treatment. Research has indicated CKD has a strong heritable component, but this is not fully understood. The kidneys are dependent upon aerobic respiration which occurs in the mitochondria; therefore, it is possible that mitochondrial genomic variants could result in renal dysfunction. This project aims to identify genomic features associated with CKD, and also to assess the computational tools currently available for use in such studies and to develop new computational tools.<br><br> 2026-10-01T16:48:27Z Text Thesis 10.17034/32637846.v1 https://figshare.com/articles/thesis/Bioinformatic_and_genomic_analyses_to_identify_mitochondrial_genomic_features_associated_with_chronic_kidney_disease/32637846 All Rights Reserved