2026-10-12T10:55:41Z https://api.figshare.com/v2/oai

oai:figshare.com:article/32598366 2026-09-16T07:02:10Z category_1 category_666 portal_81 item_type_3 month_year_09_2026

Molecular basis for cold and menthol sensing by mammalian TRPM8 Seok-Yong Lee (21714560) Hyuk-Joon Lee (19708692) Cheon-Gyu Park (21714569) Justin Fedor (21714563) Wyatt Peele (24144975) Mario Borgnia (24144978) Biophysics Structural Biology (incl. Macromolecular Modelling) TRPM 8 Channel Activation Induced Cold Sensation menthol mouse TRPM8. cryo-EM maps and models. C stands for the closed state, O stands for an open state, Pre-O stands for a pre-open state. C1A_4C (C1 closed state, AITC bound, and 4C). C1M_4C (C1 closed state, Menthol bound, and 4C). C2M_4C (C2 closed state, menthol bound, 4C), OM_4C (open state, menthol bound, 4C). pre-OM_20C (pre open state, menthol bound, 20C). 2026-09-16T07:02:10Z Dataset Dataset 10.6084/m9.figshare.32598366.v1 https://figshare.com/articles/dataset/Molecular_basis_for_cold_and_menthol_sensing_by_mammalian_TRPM8/32598366 CC BY 4.0