2026-10-06T07:25:34Z https://api.figshare.com/v2/oai

oai:figshare.com:article/32415666 2026-10-05T16:30:44Z category_24271 category_24313 category_24208 category_24748 category_24244 item_type_3 month_year_10_2026

<b>From Ancient Amine Handling to Specialized Histaminergic Signaling: A Phylogenomic Study Across Metazoa</b> (Supplementary Dataset) Ankit Thakur (23217868) Mahesh Kulharia (23217823) Phylogeny and comparative analysis Molecular evolution Bioinformatics and computational biology not elsewhere classified Neurosciences not elsewhere classified Animal systematics and taxonomy histamina evolution neurobiology phylogency <p dir="ltr">Our study reconstructs the evolutionary history of the histaminergic signaling system across 89 proteomes spanning major metazoan lineages to determine how its molecular components emerged and diversified. Using homology searches and inferences, domain validation, phylogenetic reconstruction, rogue taxon filtering, and gene tree–species tree reconciliation, we analyzed core gene families involved in histamine biosynthesis , degradation vesicular and membrane transport, and signaling.</p> 2026-10-05T16:30:44Z Dataset Dataset 10.6084/m9.figshare.32415666.v3 https://figshare.com/articles/dataset/_b_From_Ancient_Amine_Handling_to_Specialized_Histaminergic_Signaling_A_Phylogenomic_Study_Across_Metazoa_b_Supplementary_Dataset_/32415666 CC BY 4.0