2026-10-15T09:41:33Z https://api.figshare.com/v2/oai

oai:figshare.com:article/32123779 2026-05-11T06:33:16Z category_25072 category_25075 category_25096 category_25084 category_25087 portal_753 item_type_3 month_year_05_2026

Bio-guided purification of compounds from South African medicinal plants traditionally used to treat inflammation Sibusiso Rali (23809852) Analytical spectrometry Bioassays Separation science Instrumental methods (excl. immunological and bioassay methods) Metabolomic chemistry Anti-cancer therapeutic agents HPLC-MS system NMR spectroscopic interpretation a549 cells growth RAW 264.7 macrophage Anti cancer activities Anti-inflammatory Solid-phase extraction (SPE) Liquid-liquid extraction 4 Bioguided-fractionation UPLC-DAD-qTOF-MS/MS SDG 9 Industry, innovation and infrastructure <p dir="ltr">Bio-guided identification and purification of anti-cancer and anti-inflammatory compounds from South African medicinal plants traditionally used to treat inflammation, with structural elucidation using UPLC-MS and NMR. This study applied solid-phase extraction (SPE) fractionation, coupled with high-throughput screening of extracts and fractions using advanced analytical tools, to isolate bioactive metabolites. From a list of 51 medicinal plants, three promising species were selected for further purification using HPLC-based methods. The compounds were identified using UPLC-QTOF-MS analysis, followed by comprehensive structural elucidation using nuclear magnetic resonance (NMR) spectroscopy.</p> 2026-05-11T06:33:16Z Dataset Dataset 10.25403/UPresearchdata.32123779.v3 https://figshare.com/articles/dataset/Bio-guided_purification_of_compounds_for_South_African_medicinal_plants_traditionally_used_to_treat_inflammation/32123779 CC BY 4.0