This atlas captures the full theoretical degradome of ferritin by predicting enzymatic and chemical cleavage sites and enumerating every possible contiguous peptide fragment. For each fragment, detailed biochemical and biophysical properties are computed, including mass-to-charge ratio, molecular weight, Boman index, net charge, isoelectric point, hydrophobicity, instability index, and aliphatic index. All peptide-level information is provided as structured CSV files suitable for downstream statistical analysis, proteomics workflows, and computational biology pipelines.
The resource includes:
The Ferritin Degradome Foundation Atlas is intended to support biomarker discovery, neuroimmunology, autoimmune disease research, neurodegenerative disease proteomics, therapeutic target development, autoantibody and cleavage-pattern analyses, and machine-learning applications. As new cleavage sites, mutations, or biological variants are identified, the atlas will be updated to expand its scope and translational value
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